Rejuran Microneedling vs Injections: What’s the Difference and Which One Is Right for You?

Rejuran is well known for its ability to repair the skin, boost collagen, and improve overall skin health. But there are now multiple ways to deliver it, either through direct injections or by using microneedling devices.

If you’ve seen both options offered at different clinics and are unsure which one to go for, this guide breaks down the key differences, benefits, and ideal use cases for each method.

What Is Rejuran Made Of?

Before comparing techniques, it’s helpful to know what Rejuran actually is. Rejuran is made from polynucleotides (PN) extracted from salmon DNA. These molecules have strong regenerative properties that help:

• Repair damaged skin

• Reduce inflammation

• Stimulate collagen and elastin production

• Improve skin texture and hydration

Rejuran is not a filler. Its goal is to improve skin quality over time by encouraging natural healing processes from within.

Rejuran Injections: Precise and Targeted Delivery

This is the original and most common form of Rejuran treatment. A trained doctor or nurse uses a fine needle to inject small amounts of the product into the superficial dermis layer of the skin. This often creates small, raised bumps that settle within 24 to 72 hours.

Benefits of Rejuran Injections:

• Precise placement allows for targeted treatment, especially effective under the eyes or around fine lines

• Stronger regenerative effect because the product is delivered exactly where it needs to act

• Suitable for deeper concerns such as acne scarring, skin laxity, or under-eye hollowness

• Longer-lasting results when done as part of a full three-session protocol

This is the method we use at TT Aesthetics, where sessions are spaced one month apart to allow the skin to fully regenerate between treatments.

Rejuran Microneedling: Broader and Less Invasive

This method uses a microneedling pen or stamp to create micro-channels in the skin, followed by the topical application of Rejuran. The serum is absorbed into the skin through the micro-openings.

Benefits of Rejuran Microneedling:

• Less invasive and generally more comfortable

• Minimal downtime, with redness usually settling within 24 hours

• Great for improving overall skin texture, dullness, and fine lines

• Ideal for beginners or those with very low pain tolerance

While microneedling with Rejuran still offers visible improvement, the absorption is more superficial compared to direct injections, which can reduce the intensity and longevity of the results.

Which One Is Right for You?

The best method depends on your skin goals, concerns, and comfort level.

Choose Rejuran Injections if:

• You have deeper skin concerns like acne scars or under-eye hollowness

• You want a stronger regenerative effect

• You’re comfortable with a few days of downtime involving mild swelling or bumps

Choose Rejuran Microneedling if:

• Your main concern is dullness, fine lines, or uneven texture

• You prefer minimal downtime

• You’re new to skin treatments and want a gentler introduction

Final Thoughts

Both methods deliver the healing power of Rejuran, but in different ways. Injections offer more precision and deeper skin rejuvenation, while microneedling provides a gentle, glow-boosting option with quicker recovery.

At TT Aesthetics, we offer Rejuran treatments tailored to your skin needs. Whether you're considering injections or a microneedling approach, we’ll help you make the right choice for your goals and comfort.

Book a consultation to find out which method is best suited for your skin.

To learn more or to book a consultation with a qualified expert, book TT Aesthetics.