Rejuran Side Effects: What’s Normal and When to Worry

If you're thinking about trying Rejuran, it's natural to feel a little nervous about the side effects. You may have seen photos of tiny bumps or heard stories about post-treatment breakouts. The good news is that most reactions are temporary and expected. Still, it’s important to know the difference between what’s normal and what might need attention.

This guide walks you through common post-treatment side effects, how long they typically last, and when it’s worth contacting your clinic.

Common and Normal Side Effects After Rejuran

Here are the most typical reactions you can expect within the first 24 to 72 hours:

1. Redness and Swelling
Redness and light swelling are completely normal. They appear around the injection sites and are part of your body’s natural response to the micro-injuries created during treatment. Most swelling is mild and settles within 24 to 48 hours. In more sensitive areas like under the eyes, it may take slightly longer to resolve.

2. Small Bumps or "Mosquito Bites"
Rejuran is injected into the superficial layer of the skin, which often causes small raised bumps to form immediately after the procedure. These typically flatten within one to three days as the product spreads and absorbs.

3. Mild Bruising
Bruising is common and varies depending on your skin type, the area treated, and your body’s healing response. It often appears the day after treatment and fades over the next few days. Areas with thinner skin, like the under-eyes, are more prone to bruising. Applying cold compresses and avoiding blood-thinning supplements before treatment can help reduce this risk.

4. Temporary Sensitivity or Itchiness
Some clients experience mild itching, tightness, or tingling, especially on the first night. This usually fades within a few hours and is a sign of your skin's healing response.

5. Tiny Pimples or Texture Changes
Occasionally, small whiteheads or texture changes can appear a few days after treatment. These tend to be short-lived and often resolve on their own with gentle skincare and good hygiene.

When to Contact Your Clinic

Most side effects are harmless and clear up within a few days. However, it’s best to check in with your practitioner if you notice any of the following:

1. Worsening or Persistent Swelling
Mild swelling is normal, but if it becomes painful, worsens after 48 hours, or spreads significantly, it may be worth reviewing with your clinic.

2. Deep or Spreading Redness
If the redness intensifies or begins to spread beyond the treated areas, it could be a sign of inflammation or infection.

3. Hard Lumps That Don’t Settle
While temporary firmness is common, any hard lumps that remain after a week or two should be reviewed, especially if they feel uncomfortable.

4. Signs of Infection
Heat, yellow discharge, fever, or increasing pain can indicate infection and should be addressed quickly by a medical professional.

5. Allergic Reaction
Although rare, symptoms such as facial swelling, hives, or difficulty breathing should be treated as urgent. Let your clinic know about any allergies before your appointment to reduce risk.

How to Support Healing After Rejuran

Proper aftercare can reduce side effects and support smoother recovery:

• Avoid touching or massaging the treated area for 12 to 24 hours

• Skip makeup for the first day

• Use gentle, hydrating skincare

• Avoid sun exposure, saunas, or intense workouts for at least 48 hours

• Apply a cold compress if swelling or bruising appears

• Sleep with your head slightly elevated the first night

Final Thoughts

Redness, swelling, bruising, and small bumps are all part of the normal healing process after Rejuran. Most of these effects are mild and temporary, and they tend to fade within a few days. Understanding what’s expected can help you feel more confident and prepared.

If anything feels unusual or uncomfortable, don’t hesitate to reach out to your clinic. A quick follow-up can provide peace of mind and help ensure you’re healing as expected.

For questions or to book your consultation, get in touch with the team at TT Aesthetics.